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Chemical Name: (E)-4-((4-(4-(1H-1
including ERK1/2
Smiles: O=S1(=O)N=C(NC2=CC=CC=C2N2CCCC2)C2=CC=CC=C12
3-H)propan-2-yl]pyrimidin-5-yl]-3
5-trien-1-yl)-1
Asenapine 0289 Chemical Name: (E)-4-((4-(4-(1H-1Asenapine, also known as Org 5222 and HSDB 8061, shows high affinity (pKi) for numerous receptors, including the serotonin 5 HT1A (8. 6), 5 HT1B (8. 4), 5 HT2A (10. 2), 5 HT2B (9. 8), 5 HT2C (10. 5), 5 HT5A (8. 8), 5 HT6 (9. 5), and 5 HT7 (9. 9) receptors, the adrenergic 1 (8. 9), 2A (8. 9), 2B (9. 5), and 2C (8. 9) receptors, the dopamine D1 (8. 9), D2 (8. 9), D3 (9. 4), and D4 (9. 0) receptors, and the histamine H1 (9. 0) and H2 (8. 2) receptors.
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