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BAN ORL 24 dihydrochloride Size:Contact [email protected] for quotation Smiles: CN(CC1=CSC(=N1)C(C)C)C(=O)N[C@@H](CCN1CCOCC1)C(=O)N[C@@H](CC1C=CC=CC=1)CC[C@H](CC1C=CC=CC=1)NC(=O)OCC1=CN=CS1

SKU: 40167402154

4.2
USD100.00 USD138.00

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Description

Smiles: CN(CC1=CSC(=N1)C(C)C)C(=O)N[C@@H](CCN1CCOCC1)C(=O)N[C@@H](CC1C=CC=CC=1)CC[C@H](CC1C=CC=CC=1)NC(=O)OCC1=CN=CS1

CAS Number: 749886-87-1

24 hours) significant increases of 2 to 5-fold in chemokine and pro-inflammatory expression

4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol

35)12-38)45-25-9-23(39-13-30(36

BAN ORL 24 dihydrochloride Size:Contact [email protected] for quotation Smiles: CN(CC1=CSC(=N1)C(C)C)C(=O)N[C@@H](CCN1CCOCC1)C(=O)N[C@@H](CC1C=CC=CC=1)CC[C@H](CC1C=CC=CC=1)NC(=O)OCC1=CN=CS1BAN ORL 24 is a potent and selective NOP receptor antagonist. (IC50 values are 0. 27, 2500, 6700 and > 10000 nM for NOP, , and receptors respectively). IC50 value: 0. 27 nM Target: NOP receptor BAN ORL 24 inhibits nociceptin induced stimulation of [35S] GTPS binding and Ca2+ mobilization in CHO cells in vitro. BAN ORL 24 antagonizes NOP agonist induced reduction in locomotor activity in vivo. Brain penetrant. Product information CAS Number: 1401463 54

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