SJF 1521 - EGFR Degrader. CAS# 2230821-40-4 size:2mg solid 01-100 μM

01-100 μM

Smiles: COCCN(C)C1C=CC(=CC=1)NC(=O)C1N=C(OC=1C(F)(F)F)C1C=CC=CC=1

is non-toxic in SCID mice

111(42):15072-7

is a potential first-in-class treatment for type 2 diabetes that targets G protein-coupled receptor 119 (GPR119)

SJF 1521 - EGFR Degrader. CAS# 2230821-40-4 size:2mg solid 01-100 μMSJF 1521, EGFR Degrader, CAS No. 2230821 40 4, is a selective EGFR Degrader. It induces degradation of EGFR in OVCAR8 cells. Product information CAS Number: 2230821 40 4 Molecular Weight: 1074. 65 Formula: C57H61ClFN7O9S Synonym: SJF 1521 SJF1521 Chemical Name: (2S,4R) 1 ((S) 2 (tert butyl) 14 (4 (4 ((3 chloro 4 ((3 fluorobenzyl)oxy)phenyl)amino)quinazolin 6 yl)phenoxy) 4 oxo 6,9,12 trioxa 3 azatetradecanoyl) 4 hydroxy N (4 (4 methylthiazol 5