This is far too specific to include in something like a Commander deck, and theres infinitely better sideboard tech out there for other formats
from a draft perspective, you take them if theyre good, pass them if theyre not
If it gave ALL your creatures indestructible, then MAYBE it might see play in EDH
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Slime Against Humanity joins the illustrious club of Can Run More Than One of This Card In Commander along with Relentless Rats, Shadowborn Apostle and Persistent Petitioners, among others
