ROCK2-IN-2 line 13C3 mesylate racemic Male Sprague-Dawley rats are dosed

Male Sprague-Dawley rats are dosed with the same IV (1 mg/kg) and PO (5

MD-224 effectively induces rapid degradation of MDM2 at concentrations <1 nM in human leukemia cells

Delanzomib (CEP-18770) inhibits endothelial cell survival

Formula: C68H109N17O22S2

It is more stable in solution than Wortmannin

ROCK2-IN-2 line 13C3 mesylate racemic Male Sprague-Dawley rats are dosedROCK2 IN 2 is a selective ROCK2 inhibitor extracted from patent US20180093978A1, Compound A 30, has an IC50 of <1 M. Product information CAS Number: 1995065 79 6 Molecular Weight: 360. 39 Formula: C18H12N6OS Chemical Name: N {5 [3 (1, 3 oxazol 2 yl)phenyl] 1, 3, 4 thiadiazol 2 yl} 1H indazol 5 amine Smiles: C1=C2C=NNC2=CC=C1NC1=NN=C(S1)C1=CC(=CC=C1)C1=NC=CO1 InChiKey: WFSHRQCWPPIEIB UHFFFAOYSA N InChi: InChI=1S C18H12N6OS c1 2 11(16 19 6 7 25 16)8