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Hantschel O
is a bactericidal drug that inhibits bacterial DNA gyrase and topoisomerase IV
4-b]indole
to assess the anti-tumor activity of Salinomycin
a potent antagonist of the P2X7-receptor
AMG 925 altirelin Hantschel OFLX925, also known as AMG 925, is a potent and selective type 1 inhibitor of FLT3 that retains its cellular potency against clinically relevant secondary resistance mutations in FLT3 occurring with quizartinib or sorafenib treatment (FLX925 IC50: MOLM13ITD, 15 nM; MOLM13ITD D835, 28 nM; MV4 11ITD, 16 nM; MV4 11ITD D835, 19 nM; MV4 11ITD N841, 16 nM; MV4 11ITD F691, 73 nM). Product information CAS Number: 1401033 86 0 Molecular Weight: 471. 55 Formula:
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