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Discovery of CX-5461
PFI-2 has been shown to bind to SETD7 by ITC (Kd=18nM)
and serves as a basis for new selective inhibitors of other HDAC isoforms
Ulixertinib
23)24)30-20(26-17)14-6-4-3-5-7-14/h3-11H
WAY-200070 - CAS# 440122-66-7 Catalog No.:M6587-10 Discovery of CX-5461WAY 200070, CAS No. 440122 66 7, is a selective ER receptor agonist that displays 68 fold selectivity over ER (EC50 values are 2 and 155 nM for ER and ER respectively). WAY 200070 displays antianxiolytic and antidepressive effects in vivo. Product information CAS Number: 440122 66 7 Molecular Weight: 306. 11 Formula: C13H8BrNO3 Synonym: WAY 200070 WAY 200070 WAY200070 Chemical Name: 4 (7 bromo 5 hydroxy 3H 1,3 benzoxazol 2 ylidene)cyclohexa 2,5 dien 1
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