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NE 52-QQ57 - CAS# 1401728-56-0 size:10mg solid Oral drug administration of 5

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Description

Oral drug administration of 5 mg/kg of AT13148 results in complete bioavailability

NE 52-QQ57 - CAS# 1401728-56-0 size:10mg solid Oral drug administration of 5NE 52 QQ57, CAS No. 1401728 56 0, is an orally available GPR4 antagonist with an IC50 of 70 nM. NE 52 QQ57 significantly inhibited the AGE induced increased expression of several key inflammatory cytokines and signaling molecules, including tumor necrosis factor (TNF ), interleukin (IL) 1, IL 6, inducible nitric oxide synthase (iNOS), nitric oxide (NO), cyclooxygenase 2 (COX2), and prostaglandin E2 (PGE2). Product information CAS Number: 1401728 56 0

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